Gilean McVean

Gil McVean
Institutions University of Oxford, University of Edinburgh
Alma mater University of Cambridge
Doctoral advisor Laurence Hurst[1]
Other academic advisors Brian Charlesworth and Deborah Charlesworth
Doctoral students Adam Auton, Niall Cardin, Ella Chase, Jo Gay, Chris Hallsworth, Loukas Moutsianas, Chris Spencer, Daniel Wilson[2]
Notable awards Crick Lecture 2010[3]

Gilean "Gil" McVean is a professor of statistical genetics at the University of Oxford[4] and a fellow of Linacre College, Oxford. He is a member of the 1000 Genomes Project steering committee.

Education and employment

McVean completed his PhD in the Department of Genetics, at the University of Cambridge with Laurence Hurst[5][6] in 1997.[7] He then completed a postdoc at the University of Edinburgh under the supervision of Brian Charlesworth and Deborah Charlesworth.[8] From 2000-2004 he was a Royal Society University Research Fellow, in the Department of Statistics at Oxford, where he has also been a University lecturer in Mathematical Genetics since 2004.

His research[9] focuses on population genetics and evolutionary biology including the International HapMap Project,[10][11] recombination rates in the human genome[12] and the 1000 Genomes Project.[13][14]

References

  1. ^ Hurst, L.; McVean, G. (1996). "A difficult phase for introns-early. Molecular evolution". Current biology : CB 6 (5): 533–536. doi:10.1016/S0960-9822(02)00535-3. PMID 8805261.  edit
  2. ^ http://www.stats.ox.ac.uk/~mcvean/group.html McVean group members
  3. ^ http://royalsociety.org/awards/francis-crick-lecture/ Crick Lectures
  4. ^ http://www.stats.ox.ac.uk/~mcvean/ McVean Group at the University of Oxford
  5. ^ McVean, G.T.; Hurst, L.D. (1997). "Evidence for a selectively favourable reduction in the mutation rate of the X chromosome". Nature 386 (6623): 388–392. doi:10.1038/386388a0. PMID 9121553.  edit
  6. ^ Hurst, L.D.; McVean, G.T. (1996). "... And scandalous symbionts". Nature 381 (6584): 650–651. doi:10.1038/381650a0. PMID 8649507.  edit
  7. ^ http://www.stats.ox.ac.uk/people/academic_staff/gilean_mcvean Gilean McVean Oxford University
  8. ^ Charlesworth, D.; Charlesworth, B.; McVean, G. (2001). "Genome sequences and evolutionary biology, a two-way interaction". Trends in ecology & evolution 16 (5): 235–242. doi:10.1016/S0169-5347(01)02126-7. PMID 11301152.  edit
  9. ^ http://scholar.google.com/scholar?q=gilean+mcvean Gilean McVean in Google Scholar
  10. ^ Frazer, K.A.; Ballinger, D.G.; Cox, D.R.; Hinds, D.A.; Stuve, L.L.; Gibbs, R.A.; Belmont, J.W.; Boudreau, A. et al. (2007). "A second generation human haplotype map of over 3.1 million SNPs". Nature 449 (7164): 851–861. doi:10.1038/nature06258. PMC 2689609. PMID 17943122. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2689609.  edit
  11. ^ Sabeti, P.C.; Varilly, P.; Fry, B.; Lohmueller, J.; Hostetter, E.; Cotsapas, C.; Xie, X.; Byrne, E.H. et al. (2007). "Genome-wide detection and characterization of positive selection in human populations". Nature 449 (7164): 913–918. doi:10.1038/nature06250. PMC 2687721. PMID 17943131. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2687721.  edit
  12. ^ McVean, G. A. T.; Myers, S.; Hunt, S.; Deloukas, P.; Bentley, D.; Donnelly, P. (2004). "The Fine-Scale Structure of Recombination Rate Variation in the Human Genome". Science 304 (5670): 581–584. doi:10.1126/science.1092500. PMID 15105499.  edit
  13. ^ Danecek, P.; Auton, A.; Abecasis, G.; Albers, C. A.; Banks, E.; Depristo, M. A.; Handsaker, R.; Lunter, G. et al. (2011). "The Variant Call Format and VCFtools". Bioinformatics. doi:10.1093/bioinformatics/btr330. PMID 21653522.  edit
  14. ^ Hernandez, R. D.; Kelley, J. L.; Elyashiv, E.; Melton, S. C.; Auton, A.; McVean, G.; Sella, G.; Przeworski, M. et al. (2011). "Classic Selective Sweeps Were Rare in Recent Human Evolution". Science 331 (6019): 920–924. doi:10.1126/science.1198878. PMID 21330547.  edit